The offences included murder, attempted murder, rape, assault, drug dealing, possession of drugs, illegal possession of firearms and ammunition, burglary, illicit mining and illegal trading in liquor.
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Police also arrested illegal migrants and wanted suspects linked to various crimes.
During the operation, police conducted stop-and-search operations, roadblocks, patrols, tracing operations and compliance inspections, Mpumalanga police spokesperson Sergeant Thulisile Magagula says.
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Police further confiscated and recovered firearms, ammunition, drugs, counterfeit goods, precious metals, vehicles, illegal cigarettes, liquor and dangerous weapons.
